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Dr. Jonathan Vande Geest leads the Soft Tissue Biomechanics Laboratory (STBL) whose primary goal is to develop and utilize novel experimental and computational bioengineering approaches to study the structure function relationships of soft tissues in human growth, remodeling, and disease. The STBL has also devoted significant effort in the development of novel endovascular medical devices. Advances in bioengineering are established in the STBL by seamlessly bringing together state-of-the-art techniques in tissue fabrication, nonlinear optical microscopy, finite element modeling, and cell mechanobiology. Current projects in the STBL are focused on neurodegenerative diseases including primary open angle glaucoma and vocal fold paralysis, as well as the development of a compliance matched tissue engineered vascular graft.