Publications

PubMed

Google Scholar

  1. Liou, J.J., Drewry, M.D., Sweeney, A., Brown, B.N., & Vande Geest, J.P. (2020) Decellularizing the Porcine Optic Nerve Head: Toward a Model to Study the Mechanobiology of Glaucoma. Translational Vision Science & Technology, 9(8):17. doi: 10.1167/tvst.9.8.17.
  2. Liou, J.J., Shoemaker, J.E., & Vande Geest, J.P. (2020) Mechanobiology of the Optic Nerve Head in Primary Open-Angle Glaucoma. Mechanobiology, 47-64. doi: 10.1016/B978-0-12-817931-4.00003-0.
  3. Ardila, D.C., Liou, J.J., Maestas, D., Slepian, M.J., Badowski, M., Wagner, W.R., Harris, D., & Vande Geest, J.P. (2019). Surface modification of electrospun scaffolds for endothelialization of tissue-engineered vascular grafts using human cord blood-derived endothelial cells. Journal of Clinical Medicine, 8(2). doi: 10.3390/jcm8020185.
  4. Ardila, D.C., Tamimi, E., Doetschman, T., Wagner, W.R., & Vande Geest, J.P. (2019). Modulating smooth muscle cell response by the release of TGF beta 2 from tubular scaffolds for vascular tissue engineering. Journal of Controlled Release, 299, 44-52. doi: 10.1016/j.jconrel.2019.02.024.
  5. Behkam, R., Kollech, H.G., Jana, A., Hill, A., Danford, F., Howerton, S., Ram, S., Rodriguez, J.J., Utzinger, U., Girkin, C.A., & Vande Geest, J.P. (2019). Racioethnic differences in the biomechanical response of the lamina cribrosa. Acta Biomaterialia, 88, 131-140. doi: 10.1016/j.actbio.2019.02.028.
  6. Kollech, H.G., Ayyalasomayajula, A., Behkam, R., Tamimi, E., Furdella, K., Drewry, M., & Vande Geest, J.P. (2019). A subdomain method for mapping the heterogeneous mechanical properties of the human posterior Sclera. Frontiers in Bioengineering and Biotechnology, 7,129. doi: 10.3389/fbioe.2019.129.
  7. Tamimi, E.A., Ardila, D.C., Ensley, B.D., Kellar, R.S., & Vande Geest, J.P. (2019). Computationally optimizing the compliance of multilayered biomimetic tissue engineered vascular grafts. J Biomech Eng, 141(6). doi: 10.1115/1.4042902.
  8. Ram, S., Danford, F., Howerton, S., Rodriguez, J.J., & Vande Geest, J.P. (2018). Three-dimensional segmentation of the ex-vivo anterior lamina cribrosa from second-harmonic imaging microscopy. IEEE Transactions on Biomedical Engineering, 65(7), 1617-1629. doi: 10.1109/TBME.2017.2674521.
  9. Behkam, R., Roberts, K.E., Bierhals, A.J., Jacobs, M.E., Edgar, J.D., Paniello, R.C., Woodson, G., Vande Geest, J.P., & Barkmeier-Kraemer, J.M. (2017). Aortic arch compliance and idiopathic unilateral vocal fold paralysis. Journal of Applied Physiology, 123(2), 303-309. doi: 10.1152/japplphysiol.00239.2017.
  10. Furdella, K.J., Witte, R.S., & Vande Geest, J.P. (2017). Tracking delivery of a drug surrogate in the porcine heart using photoacoustic imaging and spectroscopy. Journal of Biomedical Optics, 22(4), 41016. doi: 10.1117/1.JBO.22.4.041016.
  11. Tamimi, E.A., Pyne, J.D., Muli, D.K., Axman, K.E., Howerton, S.J., Davis, M.R., Girkin, C.A., & Vande Geest, J.P. (2017). Racioethnic differences in human posterior scleral and optic nerve stump deformation. Investigative Ophthalmology & Visual Science, 58(10), 4235-4246. doi: 10.1167/iovs.17-22141.
  12. Armstrong, M.H., Tepole, A.B., Kuhl, E., Simon, B.R., & Vande Geest, J.P. (2016). a finite element model for mixed porohyperelasticity with transport, swelling, and growth. In Aliseda, A. (Ed.). PloS one, 11(4), e0152806.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0152806.
  13. Ayyalasomayajula, A., Park, R.I., Simon, B.R., & Vande Geest, J.P. (2016). A porohyperelastic finite element model of the eye: the influence of stiffness and permeability on intraocular pressure and optic nerve head biomechanics. Computer Methods in Biomechanics and Biomedical Engineering, 19(6), 591-602. doi: 10.1080/10255842.2015.1052417.
  14. Harrison, S., Tamimi, E., Uhlorn, J., Leach, T., & Vande Geest, J.P. (2016). Computationally optimizing the compliance of a biopolymer based tissue engineered vascular graft. Journal of Biomechanical Engineering-Transactions of the ASME, 138(1), 014505. doi: 10.1115/1.4032060.
  15. Haskett, D.G., Maestas, D., Howerton, S.J., Smith, T., Ardila, D.C., Doetschman, T., Utzinger, U., McGrath, D., McIntyre, J.O., & Vande Geest, J.P. (2016). 2-photon characterization of optical proteolytic beacons for imaging changes in matrix-metalloprotease activity in a mouse model of aneurysm. Microscopy and Microanalysis, 22(2), 349-360. doi: 10.1017/S1431927616000088.
  16. Tamimi, E., Ardila, D.C., Haskett, D.G., Doetschman, T., Slepian, M.J., Kellar, R.S., & Vande Geest, J.P. (2016). biomechanical comparison of glutaraldehyde-crosslinked gelatin fibrinogen electrospun scaffolds to porcine coronary arteries. Journal of Biomechanical Engineering-Transactions of the ASME, 138(1), 011001. doi: 10.1115/1.4031847.
  17. Ardila, D.C., Tamimi, E., Danford, F.L., Haskett, D.G., Kellar, R.S., Doetschman, T., & Vande Geest, J.P. (2015). TGF beta 2 differentially modulates smooth muscle cell proliferation and migration in electrospun gelatin-fibrinogen constructs. Biomaterials, 37, 164-173. doi: 10.1016/j.biomaterials.2014.10.021.
  18. Williams, M.J., Ayylasomayajula, A., Behkam, R., Bierhals, A.J., Jacobs, M.E., Edgar, J.D., Paniello, R.C., Barkmeier-Kraemer, J.M., & Vande Geest, J.P. (2015). A computational study of the role of the aortic arch in idiopathic unilateral vocal-fold paralysis. Journal of Applied Physiology, 118(4), 465-474. doi: 10.1152/japplphysiol.00638.2014.
  19. Harper, J.L., Simon, B.R., & Vande Geest, J.P. (2014). A one-dimensional mixed porohyperelastic transport swelling finite element model with growth. Journal of the Mechanical Behavior of Biomedical Materials, 29, 663-675. doi: 10.1016/j.jmbbm.2013.04.019.
  20. Pyne, J.D., Genovese, K., Casaletto, L., & Vande Geest, J.P. (2014). Sequential-digital image correlation for mapping human posterior sclera and optic nerve head deformation. Journal of Biomechanical Engineering-Transactions of the ASME, 136(2), 021002. doi: 10.1115/1.4026224.
  21. Williams, M.J., Utzinger, U., Barkmeier-Kraemer, J.M., & Vande Geest, J.P. (2014). Differences in the microstructure and biomechanical properties of the recurrent laryngeal nerve as a function of age and location. Journal of Biomechanical Engineering-Transactions of the ASME, 136(8), 081008. doi: 10.1115/1.4027682.
  22. Danford, F.L., Yan, D., Dreier, R.A., Cahir, T.M., Girkin, C.A., & Vande Geest, J.P. (2013). Differences in the region- and depth-dependent microstructural organization in normal versus glaucomatous human posterior sclerae. Investigative Ophthalmology & Visual Science, 54(13), 7922-7932. doi: 10.1167/iovs.13-12262.
  23. Haskett, D., Azhar, M., Utzinger, U., & Vande Geest, J.P. (2013). Progressive alterations in microstructural organization and biomechanical response in the ApoE mouse model of aneurysm. Biomatter, 3(3), e24648. doi: 10.4161/biom.24648.
  24. Haskett, D., Johnson, G., Zhou, A., Utzinger, U., & Vande Geest, J.P. (2013). Erratum to: Microstructural and biomechanical alterations of the human aorta as a function of age and location (vol 12, pg 413, 2013). Biomechanics and Modeling in Mechanobiology, 12(2), 413-414. doi: 10.1007/s10237-012-0415-6.
  25. Keyes, J.T., Lockwood, D.R., Simon, B.R., & Vande Geest, J.P. (2013). Deformationally dependent fluid transport properties of porcine coronary arteries based on location in the coronary vasculature. Journal of the Mechanical Behavior of Biomedical Materials, 17, 296-306. doi: 10.1016/j.jmbbm.2012.10.002.
  26. Keyes, J.T., Lockwood, D.R., Utzinger, U., Montilla, L.G., Witte, R.S., & Vande Geest, J.P. (2013). Comparisons of planar and tubular biaxial tensile testing protocols of the same porcine coronary arteries. Annals of Biomedical Engineering, 41(7), 1579-1591. doi: 10.1007/s10439-012-0679-0.
  27. Keyes, J.T., Simon, B.R., & Vande Geest, J.P. (2013). A finite element study on variations in mass transport in stented porcine coronary arteries based on location in the coronary arterial tree. Journal of Biomechanical Engineering-Transactions of the ASME, 135(6), 61008-61011. doi: 10.1115/1.4024137.
  28. Keyes, J.T., Simon, B.R., & Vande Geest, J.P. (2013). Location-dependent coronary artery diffusive and convective mass transport properties of a lipophilic drug surrogate measured using nonlinear microscopy. Pharmaceutical Research, 30(4), 1147-1160. doi: 10.1007/s11095-012-0950-y.
  29. Warren, P.D., Sycks, D.G., McGrath, D.V., & Vande Geest, J.P. (2013). Modeling the microstructurally dependent mechanical properties of poly(ester-urethane-urea)s. Journal of Biomedical Materials Research Part A, 101(12), 3382-3387. doi: 10.1002/jbm.a.34641.
  30. Haskett, D., Doyle, J.J., Gard, C., Chen, H., Ball, C., Estabrook, M.A., Encinas, A.C., Dietz, H.C., Utzinger, U., Vande Geest, J.P., & Azhar, M. (2012). Altered tissue behavior of a non-aneurysmal descending thoracic aorta in the mouse model of Marfan syndrome. Cell and Tissue Research, 347(1), 267-277. doi: 10.1007/s00441-011-1270-y.
  31. Haskett, D., Speicher, E., Fouts, M., Larson, D., Azhar, M., Utzinger, U., & Vande Geest, J.P. (2012). The effects of angiotensin II on the coupled microstructural and biomechanical response of C57BL/6 mouse aorta. Journal of Biomechanics, 45(5), 772-779. doi: 10.1016/j.jbiomech.2011.11.017.
  32. Holmes, J.W., & Vande Geest, J.P. (2012). Cardiovascular solid mechanics grows and remodels. Journal of Biomechanics, 45(5), 727. doi: 10.1016/j.jbiomech.2011.11.011.
  33. Ashton, J.H., Ayyalasomayajula, A., Simon, B.R., & Vande Geest, J.P. (2011). Wall stress reduction in abdominal aortic aneurysms as a result of polymeric endoaortic paving. Annals of Biomedical Engineering, 39(6), 1680-1689. doi: 10.1007/s10439-011-0271-z.
  34. Ashton, J.H., Mertz, J.A.M., Harper, J.L., Slepian, M.J., Mills, J.L., McGrath, D.V., & Vande Geest, J.P. (2011). Polymeric endoaortic paving: mechanical, thermoforming, and degradation properties of polycaprolactone/polyurethane blends for cardiovascular applications. Acta Biomaterialia, 7(1), 287-294. doi: 10.1016/j.actbio.2010.09.004.
  35. Keyes, J.T., Borowicz, S.M., Rader, J.H., Utzinger, U., Azhar, M., & Vande Geest, J.P. (2011). design and demonstration of a microbiaxial optomechanical device for multiscale characterization of soft biological tissues with two-photon microscopy. Microscopy and Microanalysis, 17(2), 167-175. doi: 10.1017/S1431927610094341.
  36. Keyes, J.T., Haskett, D.G., Utzinger, U., Azhar, M., & Vande Geest, J.P. (2011). Adaptation of a planar microbiaxial optomechanical device for the tubular biaxial microstructural and macroscopic characterization of small vascular tissues. Journal of Biomechanical Engineering-Transactions of the ASME, 133(7), 075001. doi: 10.1115/1.4004495.
  37. Keyes, J.T., Yan, D., Rader, J.H., Utzinger, U., & Vande Geest, J.P. (2011). A gimbal-mounted pressurization chamber for macroscopic and microscopic assessment of ocular tissues. Journal of Biomechanical Engineering-Transactions of the ASME, 133(9), 095001. doi: 10.1115/1.4004921.
  38. Vande Geest, J.P., Simon, B.R., Rigby, P.H., & Newberg, T.P. (2011). Coupled porohyperelastic mass transport (PHEXPT) finite element models for soft tissues using ABAQUS. Journal of Biomechanical Engineering, 133(4), 044502. doi: 10.1115/1.4003489.
  39. Vande Geest, J.P., Simon, B.R., Rigby, P.H., & Newberg, T.P. (2011). Coupled Porohyperelastic Mass Transport (PHEXPT) finite element models for soft tissues using ABAQUS. Journal of Biomechanical Engineering-Transactions of the ASME, 133(4), 044502. doi: 10.1115/1.4003489.
  40. Yan, D., McPheeters, S., Johnson, G., Utzinger, U., & Vande Geest, J.P. (2011). Microstructural differences in the human posterior sclera as a function of age and race. Investigative Ophthalmology & Visual Science, 52(2), 821-829. doi: 10.1167/iovs.09-4651.
  41. Alexander, M.J., Barkmeier-Kraemer, J.M., & Vande Geest, J.P. (2010). Biomechanical properties of recurrent laryngeal nerve in the piglet. Annals of Biomedical Engineering, 38(8), 2553-2562. doi: 10.1007/s10439-010-0013-7.
  42. Ayyalasomayajula, A., Polk, A., Basudhar, A., Missoum, S., Nissim, L., & Vande Geest, J.P. (2010). Three dimensional active contours for the reconstruction of abdominal aortic aneurysms. Annals of Biomedical Engineering, 38(1), 164-176. doi: 10.1007/s10439-009-9833-8.
  43. Ayyalasomayajula, A., Vande Geest, J.P., & Simon, B.R. (2010). Porohyperelastic finite element modeling of abdominal aortic aneurysms. Journal of Biomechanical Engineering-Transactions of the ASME, 132(10), 104502. doi: 10.1115/1.4002370.
  44. Haskett, D., Johnson, G., Zhou, A., Utzinger, U., & Vande Geest, J.P. (2010). Microstructural and biomechanical alterations of the human aorta as a function of age and location. Biomechanics and Modeling in Mechanobiology, 9(6), 725-736. doi: 10.1007/s10237-010-0209-7.
  45. Layman, R., Missoum, S., & Vande Geest, J.P. (2010). Simulation and probabilistic failure prediction of grafts for aortic aneurysm. Engineering Computations, 27(1-2), 84-105. doi: 10.1108/02644401011008531.
  46. Vad, S., Eskinazi, A., Corbett, T., McGloughlin, T., & Vande Geest, J.P. (2010). Determination of coefficient of friction for self-expanding stent-grafts. Journal of Biomechanical Engineering, 132(12). doi: 10.1115/1.4002798.
  47. Vad, S., Eskinazi, A., Corbett, T., McGloughlin, T., & Vande Geest, J.P. (2010). Determination of coefficient of friction for self-expanding stent-grafts. Journal of Biomechanical Engineering-Transactions of the ASME, 132(12), 121007. doi: 10.1115/1.4002798.
  48. Warren, P.D., McGrath, D.V., & Vande Geest, J.P. (2010). Effect of crosslinker length and composition on the hydrophobicity and thermomechanical response of acrylate-based shape-memory polymers. Macromolecular Materials and Engineering, 295(4), 386-396. doi: 10.1002/mame.200900348.
  49. Ashton, J.H., Vande Geest, J.P., Simon, B.R., & Haskett, D.G. (2009). Compressive mechanical properties of the intraluminal thrombus in abdominal aortic aneurysms and fibrin-based thrombus mimics. Journal of Biomechanics, 42(3), 197-201. doi: 10.1016/j.jbiomech.2008.10.024.
  50. Junkin, M., Watson, J., Vande Geest, J.P., & Wong, P.K. (2009). Template-Guided Self-Assembly of Colloidal Quantum Dots Using Plasma Lithography. Advanced Materials, 21(12), 1247. doi: 10.1002/adma.200802122.
  51. Keyes, J., Junkin, M., Wong, P.K., & Vande Geest, J.P. (2009). Computational simulation of a magnetic microactuator for tissue engineering applications. Biomedical Microdevices, 11(6), 1259-1267. doi: 10.1007/s10544-009-9345-1.
  52. Mortazavi, A.M., Simon, B.R., Stamer, W.D., & Vande Geest, J.P. (2009). Drained secant modulus for human and porcine peripapillary sclera using unconfined compression testing. Experimental Eye Research, 89(6), 892-897. doi: 10.1016/j.exer.2009.07.011.
  53. Vande Geest, J.P., Schmidt, D.E., Sacks, M.S., & Vorp, D.A. (2008). The effects of anisotropy on the stress analyses of patient-specific abdominal aortic aneurysms. Annals of Biomedical Engineering, 36(6), 921-932. doi: 10.1007/s10439-008-9490-3.
  54. Di Martino, E.S., Bohra, A., Vande Geest, J.P., Gupta, N., Makaroun, M.S., & Vorp, D.A. (2006). Biomechanical properties of ruptured versus electively repaired abdominal aortic aneurysm wall tissue. Journal of Vascular Surgery, 43(3), 570-576. doi: 10.1016/j.jvs.2005.10.072.
  55. Vande Geest, J.P., Di Martino, E.S., Bohra, A., Makaroun, M.S., & Vorp, D.A. (2006). A biomechanics-based rupture potential index for abdominal aortic aneurysm risk assessment – demonstrative application. Abdominal Aortic Aneurysm: Genetics, Pathophysiology and Molecular Biology, 1085(1), 11-21. doi: 10.1196/annals.1383.046.
  56. Vande Geest, J.P., Dillavou, E.D., Di Martino, E.S., Oberdier, M., Bohra, A., Makaroun, M.S., & Vorp, D.A. (2006). Gender-related differences in the tensile strength of abdominal aortic aneurysm. Abdominal Aortic Aneurysm: Genetics, Pathophysiology and Molecular Biology, 1085(1), 400-402. doi: 10.1196/annals.1383.048.
  57. Vande Geest, J.P., Sacks, M.S., & Vorp, D.A. (2006). The effects of aneurysm on the biaxial mechanical behavior of human abdominal aorta. Journal of Biomechanics, 39(7), 1324-1334. doi: 10.1016/j.jbiomech.2005.03.003.
  58. Vande Geest, J.P., Sacks, M.S., & Vorp, D.A. (2006). A planar biaxial constitutive relation for the luminal layer of intra-luminal thrombus in abdominal aortic aneurysms. Journal of Biomechanics, 39(13), 2347-2354. doi: 10.1016/j.jbiomech.2006.05.011.
  59. Vande Geest, J.P., Wang, D.H.J., Wisniewski, S.R., Makaroun, M.S., & Vorp, D.A. (2006). Towards a noninvasive method for determination of patient-specific wall strength distribution in abdominal aortic aneurysms. Annals of Biomedical Engineering, 34(7), 1098-1106. doi: 10.1007/s10439-006-9132-6.
  60. Freytes, D.O., Rundell, A.E., Vande Geest, J., Vorp, D.A., Webster, T.J., & Badylak, S.F. (2005). Analytically derived material properties of multilaminated extracellular matrix devices using the ball-burst test. Biomaterials, 26(27), 5518-5531. doi: 10.1016/j.biomaterials.2005.01.070.
  61. Vorp, D.A., & Vande Geest, J.P. (2005). Biomechanical determinants of abdominal aortic aneurysm rupture. Arteriosclerosis Thrombosis and Vascular Biology, 25(8), 1558-1566. doi: 10.1161/01.ATV.0000174129.77391.55.
  62. Vande Geest, J.P., Di Martino, E.S., & Vorp, D.A. (2004). An analysis of the complete strain field within FlexercellTM membranes. Journal of Biomechanics, 37(12), 1923-1928. doi: 10.1016/j.jbiomech.2004.02.022.
  63. Vande Geest, J.P., Sacks, M.S., & Vorp, D.A. (2004). Age dependency of the biaxial biomechanical behavior of human abdominal aorta. Journal of Biomechanical Engineering-Transactions of the ASME, 126(6), 815-822. doi: 10.1115/1.1824121.